生物与制药工程学院教师个人简历

个人成就及成果：

近五年代表性论文：

1. Yan Yang, Guoliang Li*, Di Wu, Jianghua Liu, Xiuting Li, Pengjie Luo, Na Hu, Honglun Wang, Yongning Wu, Recent advances on toxicity and determination methods of mycotoxins in foodstuffs[J]. Trends in Food Science & Technology, 2020, 96, 233-252. 中科院一区TOP, IF=16.3, (ESI高被引论文).

2. Yan Yang, Di Wu, Jianghua Liu, Zhuoqun Su, Lin Li, Yongning Wu, Guoliang Li*. High-efficiency enzyme-free catalyzed hairpin assembly-mediated homogeneous SERS and naked-eyes dual-mode assay for ultrasensitive and portable detection of mycotoxin. [J] Biosensors and Bioelectronics. 2022, 214, 114526. 中科院一区TOP, IF=12.6

3. Yan Yang, Zhuoqun Su, Di Wu, Jianghua Wu, Xianlong Zhang, Yongning Wu, Guoliang Li*. Low background interference SERS aptasensor for highly sensitive multiplex mycotoxin detection based on polystyrene microspheres-mediated. [J] Analytica Chimica Acta. 2022, 1218, 340000. 中科院一区TOP, IF=6.2

4. Yan Yang, Guoliang Li*, Panxue Wang, Lihua Fan, Yiheng Shi. Highly sensitive multiplex detection of foodborne pathogens using a SERS immunosensor combined with novel covalent organic frameworks based biologic interference-free Raman tags. [J] Talanta. 2022, 243, 123369. 中科院一区TOP, IF=6.1

5. Yan Yang, Guoliang Li*, Di Wu, Aying Wen, Yongning Wu, Xuxia Zhou, β-Cyclodextrin-/AuNPs-functionalized covalent organic framework-based magnetic sorbent for solid phase extraction and determination of sulfonamides[J]. Microchimica Acta, 2020, 187, 278. 中科院二区, IF=5.7

6. Yan Yang, Yiheng Shi, Xianlong Zhang, Guoliang Li, MNAzyme catalyzed signal amplification mediated lateral flow biosensor for portable and sensitive detection of mycotoxin in food samples[J]. Analytical and Bioanalytical Chemistry, 2024, 416:1057–1067, 中科院二区, IF=4.3

7. Xianlong Zhang，Yongning Wu,  Juhong Chen, Yan Yang; Guoliang Li*, Bioinspired Artificial “Clickase” for the Catalytic Click Immunoassay of Foodborne Pathogens[J]. Analytical Chemistry. 2021, 93 (6), 3217-3225. 中科院一区TOP, IF=8.008

8. Aying Wen, Guoliang Li*, Di Wu, Yanxin Yu, Yan Yang, Na Hu, Honglun Wang, Jian Chen, Yongning Wu, Sulphonate functionalized covalent organic framework-based magnetic sorbent for effective solid phase extraction and determination of fluoroquinolones. Journal of Chromatography A, 2020, 1612, 460651. 中科院二区, IF=4.601

9. Xu JW, Yan XJ, Ge X, Zhang MZ, Dang XG, Yang Yan, Xu F, Luo YL, Li GL (2021) Novel multi-stimuli responsive functionalized PEG-based co-delivery nanovehicles toward sustainable treatments of multidrug resistant tumor. Journal of Material Chemistry B 9 (5):1297-1314. 中科院二区, IF=7.571

10. Zhang Xianlong, Yang Yan, Cao juanjuan, Qi Zihe, Li Guoliang, Point-of-care CRISPR/Cas biosensing technology: A promising tool for preventing the possible COVID-19 resurgence caused by contaminated cold-chain food and packaging. Food Frontiers. Accept.

近五年主持和参与科研项目：

1. 国家自然科学基金委员会, 地区项目, 32460620, 基于aTF识别和CRISPR-DNAzyme驱动策略的四环素类抗生素多重检测技术研究，2025-01-01 至 2028-12-31, 在研, 主持

2. 甘肃省科学技术厅，青年科技基金，基于DNA响应性纳米酶驱动MNAzyme级联扩增的有机磷农药传感检测新方法研究，2024-08至2026-07，在研，主持

3. 甘肃省教育厅，高校教师创新基金项目，双酶级联扩增介导荧光传感器用于OTA的灵敏快速检测，2024-05至2026-04，在研，主持

4. 中华人民共和国科学技术部, 国家重点研发计划, 2022YFF1100800, 跨境食品危害因子快速识别及精 准测定关键技术研究, 2022-12 至 2026-12, 在研, 参与

5. 国家自然科学基金委员会, 面上项目, 22076115, 基于稳定同位素编码点击标记的环境/食品中合成甾 体类激素及其代谢物LC-MS鉴定分析技术研究, 2021-01-01 至 2024-12-31, 在研, 参与

6. 陕西省教育厅, 陕西省重点研发计划, 2023-YBNY-177, 基于微流控SERS芯片智能检测白酒中醛类风味 物质关键技术研究, 2023-01 至 2024-12, 在研, 参与

7. 陕西省教育厅, 青年创新团队建设科研计划项目, 21JP020, 食品中强极性兽药残留精准检测技术研究, 2021-01 至 2023-12, 结题, 参与

8. 陕西省教育厅, 专项科研计划项目, 20JK0529, 木霉素前体的生物合成产量提高及定量检测研究, 2020-01 至 2022-12, 结题, 参与

9. 陕西省科学技术厅, 创新人才推进计划-青年科技新星项目, 2019KJXX-010, 食品污染物精准检测技术 及其应用研究, 2019-01 至 2020-12, 结题, 参与