生物与制药工程学院教师个人简历

个人成就及成果：

主持和参与的科研项目：

       1. 甘肃省科学技术厅，甘肃省科技计划项目（青年科技基金），23JRRA1700，高山倭蛙、倭蛙及高原林蛙血红蛋白的功能适应及分子机制研究，2023-11至2025-10，在研，主持。

       2. 兰州交通大学，青年博士基金项目，2023018，青藏高原花背蟾蜍血液氧转运系统的低氧适应机制研究，2024-01至2026-12，在研，主持。

       3. 兰州大学，中央高校基本科研业务费专项资金项目，lzujbky-2019-it16，青藏高原四种蜥蜴血红蛋白适应性进化研究，2019-01至2020-12，结项，主持。

       4. 国家自然科学基金委员会，面上项目，31971416，倭蛙个体发育不同阶段对温度变化的响应，2020-01-01至2023-12-31，58万元，结项，参与。

近年发表的代表性文章：

1. Pu, P., Niu, Z., Ma, M., Tang, X., Chen, Q. Convergent high O₂ affinity but distinct ATP-mediated allosteric regulation of hemoglobins in oviparous and viviparous Eremias lizards from the Qinghai-Tibet Plateau. Animals. 2024, 14 (10): 1440.

2. Pu, P., Zhao, Y., Niu, Z., Cao, W., Zhang, T., He, J., Wang, J., Tang, X., Chen, Q. Comparison of hematological traits and oxygenation properties of hemoglobins from highland and lowland Asiatic toad (Bufo gargarizans). Journal of Comparative Physiology B. 2021, 191 (6): 1019–1029.

3. Pu, P., Lu, S., Niu, Z., Zhang, T., Zhao, Y., Yang, X., Zhao, Y., Tang, X., Chen, Q. Oxygenation properties and underlying molecular mechanisms of hemoglobins in plateau zokor (Eospalax baileyi). American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 2019, 317 (5): R696–R708.

4. Li, C.*, Chen, B.*, Langda, S.*, Pu, P.*, ..., Chen, Y., Zhou, P., Pausch, H., Wang, X. Multi-omic analyses shed light on the genetic control of high-altitude adaptation in sheep. Genomics, Proteomics & Bioinformatics. 2024, 22 (2): qzae030.

5. Ma, M.*, Pu, P.*, Niu, Z., Zhang, T., Wu, J., Tang, X., Chen, Q. A novel mechanism for high-altitude adaptation in hemoglobin of black-spotted frog (Pelophylax nigromaculatus). Frontiers in Ecology and Evolution. 2023, 11.

6. Niu, Z., Pu, P., Zhang, T., Jia, L., Li, X., Wang, H., Ma, M., Tang, X., Chen, Q. Effects of warming at embryonic and larval stages on tadpole fitness in high-altitude Rana kukunoris. Journal of Thermal Biology. 2024, 123: 103895.

7. Zhang, T., Niu, Z., He, J., Pu, P., Meng, F., Xi, L., Tang, X., Ding, L., Ma, M., Chen, Q. Potential effects of high temperature and heat wave on Nanorana pleskei based on transcriptomic analysis. Current Issues in Molecular Biology. 2023, 45 (4): 2937–2949.

8. Qi, Y., Zhang, T., Wu, Y., Yao, Z., Qiu, X., Pu, P., Tang, X., Fu, J., Yang, W. A multilevel assessment of plasticity in response to high-altitude environment for Agama lizards. Frontiers in Ecology and Evolution. 2022, 10: 845072.

9. Niu, Z., Li, M., Pu, P., Wang, H., Zhang, T., Tang, X., Chen, Q. Effects of temperature on the locomotor performance and contraction properties of skeletal muscle from two Phrynocephalus lizards at high and low altitude. Journal of Comparative Physiology B. 2021, 191 (5): 907–916.

10. He, J., Tang, X., Pu, P., Zhang, T., Niu, Z., Meng, F., Xi, L., Ma, M., Wu, J., Ma, M., Chen, Q. Influence of high temperatures and heat wave on thermal biology, locomotor performance, and antioxidant system of high-altitude frog Nanorana pleskei endemic to Qinghai-Tibet Plateau. Frontiers in Ecology and Evolution. 2021, 9: 763191.

11. Cao, W., Pu, P., Wang, J., Niu, Z., Zhang, T., He, J., Tang, X., Chen, Q. Suppressed LPS-mediated TLR4 signaling in the plateau zokor (Eospalax baileyi) compared to the bamboo rat (Rhizomys pruinosus) and rat (Rattus norvegicus). Journal of Experimental Zoology Part A: Ecological and Integrative Physiology. 2020, 333 (4): 240–251.

12. Wang, H., Tang, X., Wang, Y., Feng, Y., Pu, P., Zhao, Y., Peng, Z., Chen, Q. Function of lactate dehydrogenase in cardiac and skeletal muscle of Phrynocephalus lizard in relation to high-altitude adaptation. Asian Herpetological Research. 2018, 9 (4): .

13. 蒲鹏, 谢晓东, 白子彧, 郭雨, 古同华, 李明, 王俊斌, 孙守钧, 丁博. 禾谷类作物高效启动子分析专用载体p14781pro-GUS的构建. 江苏农业科学. 2016, 44 (8): 60–62.

14. 马丽英, 蒲鹏, 陈强, 鲁松松. 地山雀血红蛋白高原低氧适应的分子机制. 中国生物化学与分子生物学报. 2021, 37 (1): 88–101.

15. 李相涛, 王燕, 李梅, 门胜康, 蒲鹏, 唐晓龙, 陈强. 不同海拔两种沙蜥低温耐受性的比较. 四川动物. 2017, 36 (3): 300–305.

16. 丁博, 白子彧, 王俊斌, 李明, 蒲鹏, 谢晓东. 禾谷类作物T-DNA插入突变体库专用载体pBA9N的构建. 河南农业科学. 2014, 43 (7): 10–13.